| Date | Time | Away Team | Home Team | |
|---|---|---|---|---|
| Oct. 8, 2011 | 9 p.m. | Detroit Red Wings | @ | Colorado Avalanche |
| Oct. 10, 2011 | 1 p.m. | Colorado Avalanche | @ | Boston Bruins |
| Oct. 12, 2011 | 7 p.m. | Colorado Avalanche | @ | Columbus Blue Jackets |
| Oct. 13, 2011 | 7:30 p.m. | Colorado Avalanche | @ | Ottawa Senators |
| Oct. 15, 2011 | 7 p.m. | Colorado Avalanche | @ | Montreal Canadiens |
| Oct. 17, 2011 | 7 p.m. | Colorado Avalanche | @ | Toronto Maple Leafs |
| Oct. 20, 2011 | 9 p.m. | Chicago Blackhawks | @ | Colorado Avalanche |
| Oct. 22, 2011 | 8:30 p.m. | Colorado Avalanche | @ | Chicago Blackhawks |
| Oct. 26, 2011 | 10 p.m. | Colorado Avalanche | @ | Calgary Flames |
| Oct. 28, 2011 | 9 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| Oct. 30, 2011 | 8 p.m. | Los Angeles Kings | @ | Colorado Avalanche |
| Nov. 2, 2011 | 9:30 p.m. | Phoenix Coyotes | @ | Colorado Avalanche |
| Nov. 4, 2011 | 8:30 p.m. | Colorado Avalanche | @ | Dallas Stars |
| Nov. 6, 2011 | 8 p.m. | Calgary Flames | @ | Colorado Avalanche |
| Nov. 8, 2011 | 7:30 p.m. | Colorado Avalanche | @ | Detroit Red Wings |
| Nov. 10, 2011 | 9 p.m. | New York Islanders | @ | Colorado Avalanche |
| Nov. 12, 2011 | 10 p.m. | Calgary Flames | @ | Colorado Avalanche |
| Nov. 15, 2011 | 7:30 p.m. | Colorado Avalanche | @ | Pittsburgh Penguins |
| Nov. 17, 2011 | 8 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| Nov. 18, 2011 | 9 p.m. | Dallas Stars | @ | Colorado Avalanche |
| Nov. 20, 2011 | 8 p.m. | San Jose Sharks | @ | Colorado Avalanche |
| Nov. 23, 2011 | 9:30 p.m. | Vancouver Canucks | @ | Colorado Avalanche |
| Nov. 26, 2011 | 7 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| Nov. 28, 2011 | 9 p.m. | Dallas Stars | @ | Colorado Avalanche |
| Nov. 30, 2011 | 9:30 p.m. | New Jersey Devils | @ | Colorado Avalanche |
| Dec. 2, 2011 | 9 p.m. | St. Louis Blues | @ | Colorado Avalanche |
| Dec. 4, 2011 | 8 p.m. | Detroit Red Wings | @ | Colorado Avalanche |
| Dec. 6, 2011 | 10 p.m. | Colorado Avalanche | @ | Vancouver Canucks |
| Dec. 8, 2011 | 9 p.m. | Colorado Avalanche | @ | Calgary Flames |
| Dec. 9, 2011 | 9:30 p.m. | Colorado Avalanche | @ | Edmonton Oilers |
| Dec. 13, 2011 | 9 p.m. | San Jose Sharks | @ | Colorado Avalanche |
| Dec. 15, 2011 | 10:30 p.m. | Colorado Avalanche | @ | San Jose Sharks |
| Dec. 17, 2011 | 9 p.m. | Washington Capitals | @ | Colorado Avalanche |
| Dec. 19, 2011 | 9 p.m. | Philadelphia Flyers | @ | Colorado Avalanche |
| Dec. 21, 2011 | 9:30 p.m. | St. Louis Blues | @ | Colorado Avalanche |
| Dec. 23, 2011 | 9 p.m. | Tampa Bay Lightning | @ | Colorado Avalanche |
| Dec. 26, 2011 | 6 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| Dec. 27, 2011 | 9 p.m. | Winnipeg Jets | @ | Colorado Avalanche |
| Dec. 29, 2011 | 9 p.m. | Phoenix Coyotes | @ | Colorado Avalanche |
| Dec. 31, 2011 | 8 p.m. | Colorado Avalanche | @ | Anaheim Ducks |
| Jan. 2, 2012 | 10:30 p.m. | Colorado Avalanche | @ | Los Angeles Kings |
| Jan. 6, 2012 | 8:30 p.m. | Colorado Avalanche | @ | Chicago Blackhawks |
| Jan. 7, 2012 | 8 p.m. | Colorado Avalanche | @ | St. Louis Blues |
| Jan. 10, 2012 | 9 p.m. | Nashville Predators | @ | Colorado Avalanche |
| Jan. 12, 2012 | 8 p.m. | Colorado Avalanche | @ | Nashville Predators |
| Jan. 14, 2012 | 3 p.m. | Colorado Avalanche | @ | Dallas Stars |
| Jan. 16, 2012 | 4 p.m. | Colorado Avalanche | @ | Phoenix Coyotes |
| Jan. 18, 2012 | 9:30 p.m. | Florida Panthers | @ | Colorado Avalanche |
| Jan. 21, 2012 | 10:30 p.m. | Colorado Avalanche | @ | Los Angeles Kings |
| Jan. 22, 2012 | 8 p.m. | Colorado Avalanche | @ | Anaheim Ducks |
| Jan. 24, 2012 | 9 p.m. | Minnesota Wild | @ | Colorado Avalanche |
| Jan. 31, 2012 | 9:30 p.m. | Colorado Avalanche | @ | Edmonton Oilers |
| Feb. 2, 2012 | 9 p.m. | Minnesota Wild | @ | Colorado Avalanche |
| Feb. 4, 2012 | 3 p.m. | Vancouver Canucks | @ | Colorado Avalanche |
| Feb. 7, 2012 | 9 p.m. | Chicago Blackhawks | @ | Colorado Avalanche |
| Feb. 10, 2012 | 9 p.m. | Carolina Hurricanes | @ | Colorado Avalanche |
| Feb. 11, 2012 | 8 p.m. | Colorado Avalanche | @ | St. Louis Blues |
| Feb. 15, 2012 | 10 p.m. | Colorado Avalanche | @ | Vancouver Canucks |
| Feb. 17, 2012 | 9:30 p.m. | Colorado Avalanche | @ | Edmonton Oilers |
| Feb. 19, 2012 | 8:30 p.m. | Colorado Avalanche | @ | Winnipeg Jets |
| Feb. 22, 2012 | 9 p.m. | Los Angeles Kings | @ | Colorado Avalanche |
| Feb. 24, 2012 | 7 p.m. | Colorado Avalanche | @ | Columbus Blue Jackets |
| Feb. 25, 2012 | 7 p.m. | Colorado Avalanche | @ | Detroit Red Wings |
| Feb. 27, 2012 | 9 p.m. | Anaheim Ducks | @ | Colorado Avalanche |
| March 1, 2012 | 9 p.m. | Columbus Blue Jackets | @ | Colorado Avalanche |
| March 3, 2012 | 9 p.m. | Pittsburgh Penguins | @ | Colorado Avalanche |
| March 4, 2012 | 7 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| March 6, 2012 | 9 p.m. | Minnesota Wild | @ | Colorado Avalanche |
| March 8, 2012 | 8 p.m. | Colorado Avalanche | @ | Nashville Predators |
| March 10, 2012 | 3 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| March 12, 2012 | 9 p.m. | Anaheim Ducks | @ | Colorado Avalanche |
| March 14, 2012 | 7:30 p.m. | Colorado Avalanche | @ | Buffalo Sabres |
| March 15, 2012 | 7 p.m. | Colorado Avalanche | @ | New Jersey Devils |
| March 17, 2012 | 7 p.m. | Colorado Avalanche | @ | New York Rangers |
| March 20, 2012 | 9 p.m. | Calgary Flames | @ | Colorado Avalanche |
| March 22, 2012 | 10 p.m. | Colorado Avalanche | @ | Phoenix Coyotes |
| March 24, 2012 | 10 p.m. | Vancouver Canucks | @ | Colorado Avalanche |
| March 26, 2012 | 10:30 p.m. | Colorado Avalanche | @ | San Jose Sharks |
| March 28, 2012 | 10 p.m. | Colorado Avalanche | @ | Vancouver Canucks |
| March 30, 2012 | 9 p.m. | Colorado Avalanche | @ | Calgary Flames |
| April 5, 2012 | 9 p.m. | Columbus Blue Jackets | @ | Colorado Avalanche |
| April 7, 2012 | 9 p.m. | Nashville Predators | @ | Colorado Avalanche |
| Jan. 19, 2013 | 9 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| Jan. 22, 2013 | 9 p.m. | Los Angeles Kings | @ | Colorado Avalanche |
| Jan. 24, 2013 | 9 p.m. | Columbus Blue Jackets | @ | Colorado Avalanche |
| Jan. 26, 2013 | 4 p.m. | Colorado Avalanche | @ | San Jose Sharks |
| Jan. 28, 2013 | 9:30 p.m. | Colorado Avalanche | @ | Edmonton Oilers |
| Jan. 30, 2013 | 10 p.m. | Colorado Avalanche | @ | Vancouver Canucks |
| Jan. 31, 2013 | 9 p.m. | Colorado Avalanche | @ | Calgary Flames |
| Feb. 2, 2013 | 3 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| Feb. 4, 2013 | 9 p.m. | Dallas Stars | @ | Colorado Avalanche |
| Feb. 6, 2013 | 9:30 p.m. | Anaheim Ducks | @ | Colorado Avalanche |
| Feb. 11, 2013 | 9 p.m. | Phoenix Coyotes | @ | Colorado Avalanche |
| Feb. 14, 2013 | 8 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| Feb. 16, 2013 | 10 p.m. | Colorado Avalanche | @ | Edmonton Oilers |
| Feb. 18, 2013 | 3 p.m. | Nashville Predators | @ | Colorado Avalanche |
| Feb. 20, 2013 | 10 p.m. | St. Louis Blues | @ | Colorado Avalanche |
| Feb. 23, 2013 | 4 p.m. | Colorado Avalanche | @ | Los Angeles Kings |
| Feb. 24, 2013 | 8 p.m. | Colorado Avalanche | @ | Anaheim Ducks |
| Feb. 26, 2013 | 10:30 p.m. | Colorado Avalanche | @ | San Jose Sharks |
| Feb. 28, 2013 | 9 p.m. | Calgary Flames | @ | Colorado Avalanche |
| March 3, 2013 | 3 p.m. | Colorado Avalanche | @ | Columbus Blue Jackets |
| March 5, 2013 | 7:30 p.m. | Colorado Avalanche | @ | Detroit Red Wings |
| March 6, 2013 | 8 p.m. | Colorado Avalanche | @ | Chicago Blackhawks |
| March 8, 2013 | 9 p.m. | Chicago Blackhawks | @ | Colorado Avalanche |
| March 10, 2013 | 8 p.m. | San Jose Sharks | @ | Colorado Avalanche |
| March 12, 2013 | 9 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| March 14, 2013 | 8 p.m. | Colorado Avalanche | @ | Minnesota Wild |
| March 16, 2013 | 3 p.m. | Minnesota Wild | @ | Colorado Avalanche |
| March 18, 2013 | 9 p.m. | Chicago Blackhawks | @ | Colorado Avalanche |
| March 20, 2013 | 9:30 p.m. | Dallas Stars | @ | Colorado Avalanche |
| March 23, 2013 | 8 p.m. | Colorado Avalanche | @ | Dallas Stars |
| March 24, 2013 | 8 p.m. | Vancouver Canucks | @ | Colorado Avalanche |
| March 27, 2013 | 9:30 p.m. | Colorado Avalanche | @ | Calgary Flames |
| March 28, 2013 | 10 p.m. | Colorado Avalanche | @ | Vancouver Canucks |
| March 30, 2013 | 3 p.m. | Nashville Predators | @ | Colorado Avalanche |
| April 1, 2013 | 7:30 p.m. | Colorado Avalanche | @ | Detroit Red Wings |
| April 2, 2013 | 8 p.m. | Colorado Avalanche | @ | Nashville Predators |
| April 5, 2013 | 9 p.m. | Detroit Red Wings | @ | Colorado Avalanche |
| April 6, 2013 | 9 p.m. | Colorado Avalanche | @ | Phoenix Coyotes |
| April 8, 2013 | 9 p.m. | Calgary Flames | @ | Colorado Avalanche |
| April 10, 2013 | 10 p.m. | Colorado Avalanche | @ | Anaheim Ducks |
| April 11, 2013 | 10:30 p.m. | Colorado Avalanche | @ | Los Angeles Kings |
| April 13, 2013 | 3 p.m. | Vancouver Canucks | @ | Colorado Avalanche |
| April 15, 2013 | 9 p.m. | Columbus Blue Jackets | @ | Colorado Avalanche |
| April 19, 2013 | 9 p.m. | Edmonton Oilers | @ | Colorado Avalanche |
| April 21, 2013 | 8 p.m. | St. Louis Blues | @ | Colorado Avalanche |
| April 23, 2013 | 8 p.m. | Colorado Avalanche | @ | St. Louis Blues |
| April 26, 2013 | 10 p.m. | Colorado Avalanche | @ | Phoenix Coyotes |
| April 27, 2013 | 7:30 p.m. | Minnesota Wild | @ | Colorado Avalanche |
